the combination of several scientific breakthroughs into a treatment program that restores the function of older people and people who are disabled for various reasons , such as car accidents or MS.
basically it is now possible to restore the function of the organs perfectly (at least by our standards)
to re create organ tissue from stem cells and to rejuvenate people to a level where their experience and performance puts them on the top of our explorer and deep space list,
if the pension is a problem for those worried about immortal pensioners you can make a serviceable choice about weather to receive a pension or life regeneration and a limited time pension ... depending on moral grounds.
Quotes for amalgamation and assimilation that together make a revolution in function and existance for the species under humankind's mesh >
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Drugs could one day be used to reverse the muscle-wasting effects of ageing, new research suggests.
Scientists have identified a key process responsible for muscle weakening in old age and used a chemical to block it in mouse studies.
The findings could pave the way to body-building anti-ageing drugs that keep people strong and fit near the end of their lives.
A team of British and US researchers
looked at the way stem cells in muscle repair damaged tissue by dividing
and developing into numerous new muscle fibres.
Strenuous activity, such as lifting weights, results in minor damage that triggers this response and builds up muscle. The end result is bulging biceps and rippling torsos.
But as people age, muscle loses its ability to regenerate itself, leading to limbs that are puny and weak.
Studying old mice, the researchers found that the number of dormant stem cells in muscle reduces with age.
They traced the effect to excessively high levels of FGF2 (fibroblast growth factor 2) - a protein that stimulates cells to divide.
In ageing muscle, the protein was continuously awakening the dormant stem cells for no reason.
The supply of stem cells depleted over
time, so not enough were available when they really were needed. As a
result, the ability of muscle to regenerate was impaired.
The scientists found that a drug that inhibits FGF2 prevented the decline of muscle stem cells.
Treating old mice with the drug, called SU5402, dramatically improved the ability of aged muscle tissue to repair itself.
SU5402 is purely manufactured for laboratories and not licensed for therapeutic use.
But scientists hope the research, published in the latest online issue of the journal Nature, will lead to future treatments.
Senior researcher Dr Albert Basson,
from King's College London, said: 'Preventing or reversing muscle
wasting in old age in humans is still a way off, but this study has for
the first time revealed a process which could be responsible for
age-related muscle wasting, which is extremely exciting.
'The finding opens up the possibility that one day we could develop treatments to make old muscles young again. If we could do this, we may be able to enable people to live more mobile, independent lives as they age.'
Senior-author Dr Andrew Brack, from Massachusetts General Hospital in the US, said: 'Just as it is important for athletes to build recovery time into their training schedules, stem cells also need time to recuperate, but we found that aged stem cells recuperate less often.
'We were surprised to find that the events prior to muscle regeneration had a major influence on regenerative potential. That makes sense to us as humans, in terms of the need to sleep and to eat a healthy diet, but that the need to rest also plays out at the level of stem cells is quite remarkable.'
The scientists still do not know why levels of FGF2 increase with age, causing excessive activation of stem cells.
'The next step is to analyse old muscle in humans to see if the same mechanism could be responsible for stem cell depletion in human muscle fibres, leading to loss of mass and wastage,' said team member Kieran Jones, from King's College.
the revolution
(c)RS
basically it is now possible to restore the function of the organs perfectly (at least by our standards)
to re create organ tissue from stem cells and to rejuvenate people to a level where their experience and performance puts them on the top of our explorer and deep space list,
if the pension is a problem for those worried about immortal pensioners you can make a serviceable choice about weather to receive a pension or life regeneration and a limited time pension ... depending on moral grounds.
Quotes for amalgamation and assimilation that together make a revolution in function and existance for the species under humankind's mesh >
Replacing Neurons with Inhaled Stem Cells?
That is apparently the basis of a suggested “intranasal stem cell therapy”. The idea is that since many degenerative diseases of the central nervous system involve the death of neurons, such as Parkinson’s, Huntington’s, amyotrophic lateral sclerosis and Alzheimer’s, replacing the dead cells could potentially help improve the symptoms.
The idea is really still in its infancy, though. At the moment, we do not know whether grafted cells, assuming they are not simply rejected to begin with, would actually be able to truly integrate into complex neural circuitry.
Source: http://bit.ly/IPQdbf
That is apparently the basis of a suggested “intranasal stem cell therapy”. The idea is that since many degenerative diseases of the central nervous system involve the death of neurons, such as Parkinson’s, Huntington’s, amyotrophic lateral sclerosis and Alzheimer’s, replacing the dead cells could potentially help improve the symptoms.
The idea is really still in its infancy, though. At the moment, we do not know whether grafted cells, assuming they are not simply rejected to begin with, would actually be able to truly integrate into complex neural circuitry.
Source: http://bit.ly/IPQdbf
2:
A
drug that allows the brain to absorb information as easily as it did in
childhood could be used to help adults learn new languages and get
perfect pitch. The drug, valprioc acid, restores the plasticity of the
brain, helping it absorb new information in what appears to be record
time.
Read more: http://n.pr/19R1V2k via npr
Read more: http://n.pr/19R1V2k via npr
mitochondria can be rejuvenated and leads to effective energy transfer.
Hope for new anti-ageing drug after scientists reverse muscle wastage in old mice
- Chemical used to block muscle weakening in old mice
- Could lead to drug that keeps elderly strong and fit
|
Drugs could one day be used to reverse the muscle-wasting effects of ageing, new research suggests.
Scientists have identified a key process responsible for muscle weakening in old age and used a chemical to block it in mouse studies.
The findings could pave the way to body-building anti-ageing drugs that keep people strong and fit near the end of their lives.
On the horizon: Scientists are a step closer to
developing an anti-ageing drug to keep people strong and fit near the
end of their lives (file picture)
Strenuous activity, such as lifting weights, results in minor damage that triggers this response and builds up muscle. The end result is bulging biceps and rippling torsos.
But as people age, muscle loses its ability to regenerate itself, leading to limbs that are puny and weak.
Studying old mice, the researchers found that the number of dormant stem cells in muscle reduces with age.
They traced the effect to excessively high levels of FGF2 (fibroblast growth factor 2) - a protein that stimulates cells to divide.
In ageing muscle, the protein was continuously awakening the dormant stem cells for no reason.
Hope: A chemical was used to block a key process responsible for muscle weakening in mice (file picture)
The scientists found that a drug that inhibits FGF2 prevented the decline of muscle stem cells.
Treating old mice with the drug, called SU5402, dramatically improved the ability of aged muscle tissue to repair itself.
SU5402 is purely manufactured for laboratories and not licensed for therapeutic use.
But scientists hope the research, published in the latest online issue of the journal Nature, will lead to future treatments.
'The finding opens up the possibility that one day we could develop treatments to make old muscles young again'
Senior researcher Dr Albert Basson
'The finding opens up the possibility that one day we could develop treatments to make old muscles young again. If we could do this, we may be able to enable people to live more mobile, independent lives as they age.'
Senior-author Dr Andrew Brack, from Massachusetts General Hospital in the US, said: 'Just as it is important for athletes to build recovery time into their training schedules, stem cells also need time to recuperate, but we found that aged stem cells recuperate less often.
'We were surprised to find that the events prior to muscle regeneration had a major influence on regenerative potential. That makes sense to us as humans, in terms of the need to sleep and to eat a healthy diet, but that the need to rest also plays out at the level of stem cells is quite remarkable.'
The scientists still do not know why levels of FGF2 increase with age, causing excessive activation of stem cells.
'The next step is to analyse old muscle in humans to see if the same mechanism could be responsible for stem cell depletion in human muscle fibres, leading to loss of mass and wastage,' said team member Kieran Jones, from King's College.
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